Photodistributed eruptive telangiectasias: an uncommon adverse drug reaction. A retrospective case series

Mario Vaccaro; Luca Di Bartolomeo; Francesco Borgia; Caterina Longo; Federico Vaccaro; Sebastiano Gangemi; Maria Lentini; Emanuela Caradonna

doi:10.1111/ced.15343

Photodistributed eruptive telangiectasias: an uncommon adverse drug reaction. A retrospective case series

Clin Exp Dermatol. 2022 Nov;47(11):2012-2017. doi: 10.1111/ced.15343. Epub 2022 Sep 13.

Authors

Mario Vaccaro¹, Luca Di Bartolomeo¹, Francesco Borgia¹, Caterina Longo², Federico Vaccaro², Sebastiano Gangemi³, Maria Lentini⁴, Emanuela Caradonna¹

Affiliations

¹ Department of Clinical and Experimental Medicine, Dermatology, University of Messina, Messina, Italy.
² Department of Dermatology, University of Modena and Reggio Emilia, Modena, Italy.
³ School and Unit of Allergy and Clinical Immunology, Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy.
⁴ Department of Human Pathology of Adulthood and Childhood Gaetano Barresi, Unit of Pediatrics, University of Messina, Messina, Italy.

PMID: 35876166
DOI: 10.1111/ced.15343

Abstract

Drug-induced photodistributed telangiectasia (PT) is a cutaneous adverse effect (AE) resulting from the interaction of ultraviolet radiation with pharmacotherapy. Reports of PT in the literature are scarce. We report 25 cases of drug-induced PT highlighting the potential relationship between the onset of skin lesions, drug intake and photo exposure. We alert practitioners that PT is a possible dermatological phototoxic AE of many drugs.

MeSH terms

Dermatitis, Phototoxic*
Drug-Related Side Effects and Adverse Reactions*
Exanthema*
Humans
Retrospective Studies
Telangiectasis* / chemically induced
Telangiectasis* / pathology
Ultraviolet Rays