SARS-CoV-2 infection in severe asthma is associated with worsening of COVID-19 through respiratory NLRP3 inflammasome activation

Affiliations

• ¹ Department of Internal Medicine, Research Center for Pulmonary Disorders, Jeonbuk National University Medical School, Jeonju, South Korea.
• ² Research Institute of Clinical Medicine of Jeonbuk National University-Biomedical Research Institute of Jeonbuk National University Hospital, Jeonju, South Korea.
• ³ College of Veterinary Medicine and Zoonosis Research Institute, Jeonbuk National University, Iksan, South Korea.
• ⁴ Department of Otorhinolaryngology-Head and Neck Surgery, Jeonbuk National University Medical School, Jeonju, South Korea.
• ⁵ Department of Medical Informatics, Jeonbuk National University Medical School, Jeonju, South Korea.
• ⁶ Department of Life Sciences, Ewha Womans University, Seoul, South Korea.
• ⁷ Kaipharm, Seoul, South Korea.
• ⁸ National Health Insurance Service (NHIS), Wonju, South Korea.
• ⁹ Basgenbio Inc., Seoul, South Korea.
• ¹⁰ Center for Vascular Research, Institute for Basic Science (IBS), Daejeon, South Korea.
• ¹¹ Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, South Korea.