Platypnea-orthodeoxia syndrome in a patient with ongoing COVID-19

Maki Asami-Noyama; Misa Harada; Yukari Hisamoto; Taiga Kobayashi; Keiji Oishi; Nobutaka Edakuni; Tsunahiko Hirano; Tomoyuki Kakugawa; Kazuto Matsunaga

doi:10.1002/rcr2.1009

Platypnea-orthodeoxia syndrome in a patient with ongoing COVID-19

Respirol Case Rep. 2022 Jul 19;10(8):e01009. doi: 10.1002/rcr2.1009. eCollection 2022 Aug.

Authors

Maki Asami-Noyama¹, Misa Harada¹, Yukari Hisamoto¹, Taiga Kobayashi², Keiji Oishi¹, Nobutaka Edakuni¹, Tsunahiko Hirano¹, Tomoyuki Kakugawa³, Kazuto Matsunaga¹

Affiliations

¹ Department of Respiratory Medicine and Infectious Disease Yamaguchi University School of Medicine Graduate School of Medicine Ube Japan.
² Department of Radiology Yamaguchi University School of Medicine Graduate School of Medicine Ube Japan.
³ Department of Pulmonary and Gerontology Yamaguchi University School of Medicine Graduate School of Medicine Ube Japan.

Abstract

SARS-CoV-2 infection of the vascular endothelium causes excessive vasodilation. It is important in the rehabilitation of patients with COVID-19 to recognize that increased blood flow in lung lesions at the base of the lung due to vasodilation may cause V/Q mismatch and result in platypnea-orthodeoxia syndrome.

Keywords: COVID‐19; V/Q mismatch; perfusion scintigraphy; platypnea‐orthodeoxia syndrome.