Associations Between Asthma and Polycystic Ovary Syndrome: Current Perspectives

Yue Xu; Zhi-Yang Zhou; Jie-Xue Pan; He-Feng Huang

doi:10.3389/fendo.2022.936948

Associations Between Asthma and Polycystic Ovary Syndrome: Current Perspectives

Front Endocrinol (Lausanne). 2022 Jul 5:13:936948. doi: 10.3389/fendo.2022.936948. eCollection 2022.

Authors

Yue Xu¹, Zhi-Yang Zhou¹, Jie-Xue Pan¹, He-Feng Huang^{1

2

3}

Affiliations

¹ Obstetrics & Gynecology Hospital, Institute of Reproduction and Development, Fudan University, Shanghai, China.
² Shanghai Key Laboratory of Embryo Original Diseases, International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
³ Research Units of Embryo Original Diseases, Chinese Academy of Medical Sciences, Shanghai, China.

Abstract

A potential correlation between polycystic ovary syndrome (PCOS) and asthma, used to be identified as diseases originating from two independent systems, has been supported by increasing evidence. From an epidemiological perspective, mounting studies have confirmed that women suffering from PCOS exhibit increased susceptibility to asthma. Meanwhile, PCOS and asthma seem to share several mutual pathological conditions, such as metabolic disorders, hormonal fluctuation, proinflammatory state, etc. Here, we further elucidate the correlation between asthma and PCOS by focusing on the internal common pathophysiology and adverse influences on women's health. Understanding the internal connection between PCOS and asthma may shed light on developing new prevention and control strategies to fight against these conditions.

Keywords: asthma; chronic inflammation; metabolic syndrome; polycystic ovary syndrome; reproductive health.

Publication types

Review
Research Support, Non-U.S. Gov't

MeSH terms

Asthma* / epidemiology
Asthma* / etiology
Female
Humans
Polycystic Ovary Syndrome* / complications
Polycystic Ovary Syndrome* / epidemiology
Polycystic Ovary Syndrome* / metabolism
Women's Health