Inter-laboratory testing as a strategy for external quality assessment for qualitative detection of SARS-CoV-2 by real-time RT-PCR testing in India

Indian J Med Res. 2022 Jan;155(1):86-90. doi: 10.4103/ijmr.ijmr_2433_21.

Abstract

To implement the strategy of test, track and treat to tackle the ongoing COVID-19 pandemic, the number of real-time RT-PCR-based testing laboratories was increased for diagnosis of SARS-CoV-2 in the country. To ensure reliability of the laboratory results, the Indian Council of Medical Research initiated external quality assessment (EQA) by deploying inter-laboratory quality control (ILQC) activity for these laboratories by nominating 34 quality control (QC) laboratories. This report presents the results of this activity for a period of September 2020 till November 2020. A total of 597 laboratories participated in this activity and 86 per cent of these scored ≥90 per cent concordance with QC laboratories. This ILQC activity showcased India's preparedness in quality diagnosis of SARS-CoV-2.

Keywords: External quality assessment programme; SARS-CoV-2 testing; proficiency testing; quality control; real-time RT-PCR; viral research and diagnostic laboratory.

MeSH terms

  • COVID-19 Testing
  • COVID-19* / diagnosis
  • Clinical Laboratory Techniques / methods
  • Humans
  • Pandemics
  • Reproducibility of Results
  • Reverse Transcriptase Polymerase Chain Reaction
  • SARS-CoV-2* / genetics