Case report of arthritis caused by Legionella anisa and review of the literature

BMC Infect Dis. 2022 Jul 20;22(1):633. doi: 10.1186/s12879-022-07475-3.

Abstract

Background: Legionella spp. is recognized as a common cause of community acquired pneumonia, with Legionella pneumophila serogroup 1 being the most prevalent. At least 70 species are described so far but few are identified in pathogenic conditions. Data on extrapulmonary infections are scarce.

Case presentation: A 73-yar-old male with chronic lymphoid leukemia was hospitalized for an insidious wrist arthritis. Ultrasound of the wrist showed a carpal and radiocarpal fluid effusion with positive Doppler signal. While routine bacterial cultures remained sterile, 16S rRNA PCR identified Legionella anisa. Ciprofloxacin 500 mg twice a day for a period of six weeks improved arthritis with full recovery at the end of the treatment.

Conclusion: Legionella non pneumophila are a rare cause of septic arthritis especially found in immunosuppressed patients and identification of species could help clinician to adapt antibiotherapy.

Keywords: Arthritis; Case report; Legionella non pneumophila.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Arthritis, Infectious* / diagnosis
  • Arthritis, Infectious* / drug therapy
  • Arthritis, Infectious* / microbiology
  • Humans
  • Legionella* / genetics
  • Legionnaires' Disease* / microbiology
  • Male
  • RNA, Ribosomal, 16S / genetics

Substances

  • RNA, Ribosomal, 16S

Supplementary concepts

  • Legionella anisa