Robust humoral immune response after boosting in children with Multisystem Inflammatory Syndrome in Children

Arthur J Chang; Sarah Baron; Mark D Hicar

doi:10.1016/j.idcr.2022.e01569

Robust humoral immune response after boosting in children with Multisystem Inflammatory Syndrome in Children

IDCases. 2022 Jul 13:29:e01569. doi: 10.1016/j.idcr.2022.e01569. eCollection 2022.

Authors

Arthur J Chang¹, Sarah Baron¹, Mark D Hicar¹

Affiliation

¹ Department of Pediatrics, University at Buffalo, Buffalo, NY, USA.

Abstract

The exact pathogenesis of Multisystem Inflammatory Syndrome in Children (MIS-C) is unknown. Reports on response to vaccination in children who had MIS-C are lacking. Using prospectively enrolled children, we report on humoral immune responses prior to and after SARS-CoV-2 immune rechallenge. Recurrent auricular chondritis was also noted in one child.

Keywords: Auricular chondritis; Coxsackievirus; Multisystem Inflammatory Syndrome in Children; Post-vaccination myocarditis.

Publication types

Case Reports