Lysophospholipid Metabolism and Signalling in Non-Alcoholic Fatty Liver Disease

Folia Med (Plovdiv). 2022 Feb 28;64(1):7-12. doi: 10.3897/folmed.64.e59297.

Abstract

Non-alcoholic liver disease (NAFLD) constitutes a global health pandemic. It is estimated that about 25% of the world's population suffers from NAFLD. In the long-term, a subgroup of the patients can develop inflammation and fibrosis. The end result in some cases is cirrhosis and even liver-related death. The epidemiology and natural history of NAFLD lead to extreme financial costs.

Keywords: non-alcoholic fatty liver disease lysophosphatidylcholine lysophosphatidic acid lysophospholipids sphingosine 1-phosphate.

MeSH terms

  • Humans
  • Liver Cirrhosis
  • Lysophospholipids
  • Non-alcoholic Fatty Liver Disease* / epidemiology
  • Non-alcoholic Fatty Liver Disease* / metabolism

Substances

  • Lysophospholipids