Latent Tuberculosis Infection Treatment Outcomes in an At-Risk Underserved Population in Rhode Island

J Prim Care Community Health. 2022 Jan-Dec:13:21501319221111106. doi: 10.1177/21501319221111106.

Abstract

Objectives: Within the United States (US), significant racial and ethnic disparities exist in the rates of latent TB infection (LTBI) and active TB disease. A disproportionate number of TB disease cases result from untreated LTBI among individuals born outside the US. This study evaluates LTBI treatment outcomes among an underserved, at-risk population in Rhode Island.

Methods: A quantitative retrospective chart review of adult patients with a positive screening test assessed LTBI care cascade outcomes including referral, treatment initiation, and completion.

Results: Seventy-four percent of patients found to have positive screening TB tests were born outside of the US; 80% identified as Hispanic or Black and 45% spoke a preferred language other than English. Twenty-one percent of potential candidates for LTBI treatment initiated treatment.

Conclusions: Major gaps were identified in referral success and treatment initiation. Expanding LTBI treatment access into primary care settings could be a solution to improve outcomes and decrease health inequities among at-risk communities.

Keywords: Federally Qualified Health Center; LTBI; underserved.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Adult
  • Humans
  • Latent Tuberculosis* / diagnosis
  • Latent Tuberculosis* / drug therapy
  • Latent Tuberculosis* / epidemiology
  • Retrospective Studies
  • Rhode Island / epidemiology
  • Treatment Outcome
  • Tuberculin Test
  • United States
  • Vulnerable Populations