We measured antibody binding to diverse norovirus virus-like particles over 12 months in 16 children. All had maternal antibodies at 2 months, with estimated lowest levels at 5 months of age. Antibody increases after 3 months suggested natural infections. This information could guide the timing of future norovirus vaccines.
Keywords: acute gastroenteritis; antibodies; immunity; infants; multiplex Luminex assay; norovirus; vaccination.
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