The stagnation of our fight against malaria in recent years, mainly due to the development of mosquito insecticide resistance, argues for the urgent development of new weapons. The dramatic evolution of molecular tools in the last few decades led to a better understanding of parasite-mosquito interactions and coalesced in the development of novel tools namely, mosquito transgenesis and paratransgenesis. Here we provide a historical view of the development of these new tools and point to some remaining challenges for their implementation in the field.
Keywords: Biology, Ecology and Behavior; Disease transmission and blood feeding arthropods; Malaria transmission; Medical and Veterinary Entomology; Symbiotic relationships.
© 2022 The Authors. Entomological Research published by Entomological Society of Korea and John Wiley & Sons Australia, Ltd.