Influenza complications: Reporting cardiac events through a hospital surveillance system

V Quirós-González; J Á Maderuelo-Fernández; A M Haro-Pérez; D González-Calle; V Barreales-Rodríguez; J M Eiros

doi:10.1016/j.rceng.2022.05.003

Influenza complications: Reporting cardiac events through a hospital surveillance system

Rev Clin Esp (Barc). 2022 Jul 14:S2254-8874(22)00070-4. doi: 10.1016/j.rceng.2022.05.003. Online ahead of print.

Authors

V Quirós-González¹, J Á Maderuelo-Fernández², A M Haro-Pérez³, D González-Calle⁴, V Barreales-Rodríguez⁵, J M Eiros⁶

Affiliations

¹ Dirección de Planificación, Hospital Universitario 12 de Octubre, Madrid, Spain. Electronic address: victor.quiros@salud.madrid.org.
² Unidad de Investigación en Atención Primaria de Salamanca (APISAL), Instituto de investigación Biomédica de Salamanca (IBSAL), Gerencia de Atención Primaria de Salamanca, Gerencia Regional de Salud de Castilla y León (SACyL), Spain.
³ Servicio de Medicina Preventiva, Complejo Asistencial Universitario de Salamanca, Salamanca, Spain.
⁴ Servicio de Cardiología, Complejo Asistencial Universitario de Salamanca, Salamanca, Spain.
⁵ Servicio de Medicina Interna, Complejo Asistencial Universitario de Salamanca, Salamanca, Spain.
⁶ Servicio de Microbiología, Hospital Universitario Río Hortega, Valladolid, Spain.

PMID: 35843784
DOI: 10.1016/j.rceng.2022.05.003

Abstract

Background and aims: The aim of this study was to determine the complications of influenza in all adults hospitalized with this disease and, specifically, to analyze the characteristics of post-infection cardiovascular events.

Methods: This work is observational descriptive study of adults hospitalized with influenza during the 2017-2018 and 2018-2019 seasons using the specific registry of a tertiary hospital. The complications analyzed were pneumonia, multiple organ dysfunction syndrome, septic shock, acute respiratory distress syndrome, and cardiac events.

Results: A total of 928 adults with influenza required hospitalization and 303 (32.7%) presented with one or more complications. A post-influenza cardiac event occurred in 2.5% of patients; they had a higher probability of ICU admission and higher mortality. Influenza vaccination was a protective factor for cardiac events (OR 0.32; 95%CI 0.13-0.83).

Conclusions: Influenza can lead to important complications in hospitalized patients. The high mortality rate associated with post-infection cardiac events means that preventive measures, including annual influenza vaccination, need to be emphasized.

Keywords: Cardiac events; Control de la infección; Eventos cardíacos; Gripe; Infection control; Influenza; Sistemas de vigilancia; Surveillance systems; Vaccination; Vacunación.

Publication types

Case Reports