SARS-CoV-2 variant proportions in a population can be estimated through genomic sequencing of clinical specimens or wastewater samples. We demonstrate strong pairwise correlation between statewide variant estimates in Oregon, USA, derived from both methods (correlation coefficient 0.97). Our results provide crucial evidence of the effectiveness of community-level genomic surveillance.
Keywords: COVID-19; Oregon; SARS; SARS-CoV-2; United States; coronavirus; coronavirus disease; genomic surveillance; respiratory infections; severe acute respiratory syndrome coronavirus 2; viruses; wastewater surveillance; wastewater-based epidemiology; zoonoses.