Successful Treatment of Herpes Zoster Ophthalmicus Complicated by Intense Orbital Inflammation Using Laser Irradiation over the Stellate Ganglion

Intern Med. 2023 Feb 15;62(4):623-627. doi: 10.2169/internalmedicine.9503-22. Epub 2022 Jul 14.

Abstract

A 56-year-old man presented with right-sided headache and ptosis accompanied by a facial skin rash. He was diagnosed with herpes zoster ophthalmicus (HZO). Despite acyclovir and steroid therapy, the ocular symptoms worsened. Magnetic resonance imaging (MRI) revealed severe orbital inflammation and abnormal lesions in the right trigeminal nucleus and tract. The effects of re-administration of intravenous acyclovir and steroid pulse therapy were limited. Laser irradiation of the stellate ganglion (SGL) and high-dose oral prednisolone therapy were effective. Our experience suggests the efficacy of early multimodal treatment, including SGL, in treating ocular symptoms associated with HZO.

Keywords: herpes zoster ophthalmicus; ocular symptoms; spinal trigeminal nucleus and tract; stellate ganglion block; stellate ganglion laser.

Publication types

  • Case Reports

MeSH terms

  • Acyclovir / therapeutic use
  • Antiviral Agents / therapeutic use
  • Herpes Zoster Ophthalmicus* / complications
  • Herpes Zoster Ophthalmicus* / diagnosis
  • Herpes Zoster Ophthalmicus* / drug therapy
  • Humans
  • Inflammation / complications
  • Lasers
  • Male
  • Middle Aged
  • Prednisolone / therapeutic use
  • Stellate Ganglion

Substances

  • Antiviral Agents
  • Acyclovir
  • Prednisolone