Nurses' knowledge of chemotherapy-induced neutropenia and its management: a cross-sectional survey

J Cancer Res Clin Oncol. 2023 Jul;149(7):2893-2901. doi: 10.1007/s00432-022-04140-9. Epub 2022 Jul 12.

Abstract

Background: Chemotherapy-induced neutropenia (CIN) is a serious and potentially life-threatening condition that is associated with high morbidity, mortality, and healthcare costs.

Objective: This study aims to assess nurses' level of knowledge of CIN and its association with socio-demographic factors.

Methods: A cross-sectional survey design was used.

Results: Participants had a mean age of 34.1 years (SD = 7.1 years) and were predominantly female (78%) and with a bachelor's degree in nursing (95.6%). The nurses had a moderate level of knowledge about neutropenia and its management (mean total score 16.3 out of 30, SD = 3.7). Those who had a post-graduate degree (P = .048), had received an oncology educational course (P = .011), had attended a course on neutropenia (P = .007), who were working in an oncology unit (P = .002), and had more oncology experience (P = 001) were more likely to have a higher level of knowledge of CIN and its management compared to their other counterparts.

Conclusion: Based on the findings of a moderate level of knowledge of CIN among nurses, the findings call for the need for further education and training. As a long-term plan, this might be accomplished by encouraging nurses to pursue post-graduate education or oncology-specialized certification and supporting them with scholarship grants. However, deliberate plans for short courses, training and workshops on oncology or CIN are other choices with a more immediate impact on nurses' knowledge and clinical practice. Finally, integrating oncology nursing education within nursing curricula is urgently needed.

Keywords: Cancer; Chemotherapy-induced neutropenia; Neutropenia; Nurses; Oncology nursing.

MeSH terms

  • Adult
  • Antineoplastic Agents* / adverse effects
  • Clinical Competence
  • Cross-Sectional Studies
  • Female
  • Health Knowledge, Attitudes, Practice
  • Humans
  • Male
  • Neutropenia* / chemically induced
  • Nurses*
  • Surveys and Questionnaires

Substances

  • Antineoplastic Agents