A comparison of seasonal influenza and novel Covid-19 vaccine intentions: A cross-sectional survey of vaccine hesitant adults in England during the 2020 pandemic

Hum Vaccin Immunother. 2022 Nov 30;18(5):2085461. doi: 10.1080/21645515.2022.2085461. Epub 2022 Jul 11.

Abstract

We compared intention to receive the seasonal influenza vaccine with a prospective coronavirus (COVID-19) vaccine among undecided or COVID-19 vaccine hesitant individuals to better understand the underlying differences and similarities in factors associated with vaccine intention. We delivered a cross-sectional online survey in October-November 2020. We included psychological constructs and sociodemographic variables informed by theory. We conducted pairwise comparisons and multiple linear regression models to explore associations between vaccine intention and psychological constructs. We recruited 1,660 participants, where 47.6% responded that they would likely receive the influenza vaccine, 31.0% that they would probably not accept the vaccination and 21.4% were unsure. In relation to the prospective COVID-19 vaccine, 39.0% responded that they would likely receive the vaccination, 23.7% that they would probably not accept the vaccination and 37.3% were unsure. Unique factors positively associated with COVID-19 vaccine intention were: perceived knowledge sufficiency about vaccine safety, beliefs about vaccine safety, and living in an area of low deprivation. The only unique factor positively associated with influenza intention was past influenza behavior. The strongest common predictors positively associated with intention were: favorable vaccine attitudes, the anticipated regret they may feel following infection if they were not to receive a vaccine, and the expectation from family or friends to accept the vaccine. Despite overall similarities in those factors associated with vaccination intention, we identified unique influences on intention. This additional insight will help support the planning and tailoring of future immunizations programmes for the respective viruses.

Keywords: Health Belief Model; Pandemic; Theory of Planned Behavior; behavioral models; vaccination; vaccine uptake.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • COVID-19 Vaccines
  • COVID-19* / prevention & control
  • Cross-Sectional Studies
  • England / epidemiology
  • Humans
  • Influenza Vaccines*
  • Influenza, Human*
  • Intention
  • Pandemics / prevention & control
  • Seasons
  • Surveys and Questionnaires
  • Vaccination

Substances

  • Influenza Vaccines
  • COVID-19 Vaccines

Grants and funding

This paper is independent research commissioned and funded by the National Institute for Health Research Policy Research Program. The views expressed in this publication are those of the author(s) and not necessarily those of the NHS, the National Institute for Health Research, the Department of Health and Social Care or its arm’s length bodies, and other Government Departments. This project is funded by the National Institute for Health Research (NIHR) [Policy Research Unit in Behavioral Science (project reference PR-PRU1217-20501)].