Identification of a novel HLA-DRB4 allele, HLA-DRB4*01:152 in a Kuwaiti family

HLA. 2022 Nov;100(5):546-547. doi: 10.1111/tan.14737. Epub 2022 Jul 19.

Authors

Reem Ameen¹, Jeethu Anu Geo^{1

2}, Jibu Thomas²

Affiliations

¹ Medical Laboratory Sciences Department, Health Sciences Center, Kuwait University, Kuwait City, Kuwait.
² Department of Biotechnology, Karunya Institute of Technology and Sciences, Coimbatore, India.

PMID: 35815346
DOI: 10.1111/tan.14737

Abstract

One nucleotide substitution in codon 179 of HLA-DRB4*01:03:01:01 results in a novel allele HLA-DRB4*01:152.

Keywords: HLA-DRB4*01:152; HLA; next-generation sequencing; novel allele.

© 2022 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Alleles
Base Sequence
Codon
HLA-DRB1 Chains / genetics
HLA-DRB4 Chains / genetics
High-Throughput Nucleotide Sequencing*
Humans
Kuwait
Nucleotides*

Substances

Codon
HLA-DRB1 Chains
HLA-DRB4 Chains
Nucleotides