Biological roles of sulfur dioxide and sulfite in the regulation of mitochondrial viscosity

Weijie Zhang; Yunxia Lv; Hongjun Song; Fangjun Huo; Yongbin Zhang; Caixia Yin

doi:10.1039/d2cc03420d

Biological roles of sulfur dioxide and sulfite in the regulation of mitochondrial viscosity

Chem Commun (Camb). 2022 Jul 28;58(61):8524-8527. doi: 10.1039/d2cc03420d.

Authors

Weijie Zhang¹, Yunxia Lv¹, Hongjun Song², Fangjun Huo², Yongbin Zhang², Caixia Yin¹

Affiliations

¹ Key Laboratory of Chemical Biology and Molecular Engineering of the Ministry of Education, Institute of Molecular Science, Shanxi University, Taiyuan 030006, China. yincx@sxu.edu.cn.
² Research Institute of Applied Chemistry, Shanxi University, Taiyuan 030006, China.

PMID: 35801539
DOI: 10.1039/d2cc03420d

Abstract

Herein, a NIR fluorescent probe has been developed for visualization of the roles of SO₂/SO₃^2- in mitochondrial viscosity. The results showed that SO₃^2- would increase mitochondrial viscosity and decrease mitochondrial membrane potential (MMP). However, increasing SO₂ stimulation decreased mitochondrial viscosity and caused inconspicuous MMP changes.

MeSH terms

Fluorescent Dyes
Mitochondria
Sulfites*
Sulfur Dioxide*
Viscosity

Substances

Fluorescent Dyes
Sulfites
Sulfur Dioxide