Optimizing Appropriate Disposal of Unused Postoperative Opioid: What Happens to Unused Medication?

Am Surg. 2023 Nov;89(11):4395-4400. doi: 10.1177/00031348221114064. Epub 2022 Jul 7.

Abstract

Background: Increase in opioid prescribing practices has occurred with concurrent increases in the levels of abuse, addiction, and diversion of opioid pain medication. With 82.5 opioid prescriptions prescribed for every 100 U.S. citizens, the need for more effective strategies aimed at improving opioid disposal exist. Our study sought to examine the planned rates of appropriate opioid disposal after introduction of an activated charcoal home drug disposal system (Deterra®) in combination with formalized opioid disposal education.

Methods: Participants were recruited from an academic, public safety-net hospital and grouped into 3 cohorts, no formalized opioid disposal education (No Education), written and verbal patient education on appropriate opioid disposal (Education), and Deterra® in addition to formalized opioid disposal education (Deterra). Outcomes included patients reporting unacceptable methods of opioid disposal, storage of unused opiates, and patient satisfaction with disposal instructions.

Results: Reported unacceptable opioid disposal decreased from 80.6% (n = 87) in the no education group to 20% (n = 10) in the education group to 6% (n = 3) in the Deterra group (P < .001). Education decreased long-term storage of opioid medication after completion of usage from 42% (n = 36) to 2% (n = 1), P < .001. Between the education and Deterra groups, more patients felt that the disposal instructions were clear (94% (n = 47) vs 73% (n = 36), P = .006) and more followed acceptable disposal instructions (80% (n = 39) vs 94% (n = 47) P < .001).

Conclusion: Deterra® along with formal opioid disposal education increases patients reporting plans for compliance with appropriate opioid disposal.

Keywords: disposal; diversion; opioid.

MeSH terms

  • Analgesics, Opioid* / therapeutic use
  • Educational Status
  • Humans
  • Pain, Postoperative / drug therapy
  • Practice Patterns, Physicians'*

Substances

  • Analgesics, Opioid