Hydroxymethylbilane synthase (aka porphobilinogen deaminase): A novel metabolic tumor suppressor gene in hepatocellular carcinoma

J Hepatol. 2022 Oct;77(4):912-914. doi: 10.1016/j.jhep.2022.06.023. Epub 2022 Jul 5.

Authors

Antonio Fontanellas¹, Matías A Avila²

Affiliations

¹ Program of Hepatology, CIMA, University of Navarra, Pamplona, Spain; CIBERehd, ISCIII, Madrid, Spain; IdiSNA, Pamplona, Spain. Electronic address: afontanellas@unav.es.
² Program of Hepatology, CIMA, University of Navarra, Pamplona, Spain; CIBERehd, ISCIII, Madrid, Spain; IdiSNA, Pamplona, Spain. Electronic address: maavila@unav.es.

PMID: 35798130
DOI: 10.1016/j.jhep.2022.06.023

No abstract available

Publication types

Editorial
Research Support, Non-U.S. Gov't
Comment

MeSH terms

Carcinoma, Hepatocellular* / genetics
Genes, Tumor Suppressor
Humans
Hydroxymethylbilane Synthase / genetics
Hydroxymethylbilane Synthase / metabolism
Liver Neoplasms* / genetics

Substances

Hydroxymethylbilane Synthase