Macrophages absorbing cells infected with viable SARS-CoV-2 particles fail to transition into an anti-inflammatory state, potentially contributing to a damaging immune reaction linked to severe forms of COVID-19.
Keywords: COVID-19; SARS-CoV-2; efferocytosis; human; hyperinflammation; immunology; inflammation; macrophage polarization; tissue repair.
© 2022, Wang Chau and Sugimura.