Nivolumab for treating patients with occupational cholangiocarcinoma

J Hepatobiliary Pancreat Sci. 2022 Nov;29(11):1153-1155. doi: 10.1002/jhbp.1215. Epub 2022 Aug 8.

Abstract

Tanaka et al. previously reported a case in which nivolumab for recurrent occupational cholangiocarcinoma resulted in complete response persisting for 26 months after discontinuation. Afterward, in that clinical trial, nivolumab was administered to two patients for recurrence. Both patients achieved complete response, suggesting that nivolumab is effective for occupational cholangiocarcinoma.

MeSH terms

  • Bile Duct Neoplasms* / drug therapy
  • Bile Duct Neoplasms* / pathology
  • Bile Ducts, Intrahepatic / pathology
  • Cholangiocarcinoma* / drug therapy
  • Cholangiocarcinoma* / pathology
  • Humans
  • Nivolumab / therapeutic use
  • Occupational Diseases* / pathology
  • Occupational Exposure*

Substances

  • Nivolumab