Objective: To analyze the 5-year cancer relative survival rate in cancer registries of Shandong Province during 2012-2018. Methods: 399 072 new cancer cases were collected in 23 cancer registries in Shandong Province during 2012-2018. All malignant tumors (C00-C97, D45-D47), benign central nervous system tumors (D32-D33), and central nervous system tumors (D42-D43) were registered according to the 10th revision of international classification of diseases (ICD). The survival of cancer patients was obtained by passive and active follow-up. The follow-up date was December 31, 2020. The diagnostic years were divided into three periods: 2012-2014, 2015-2017 and 2018-2020. The 5-year cancer survival rates were calculated by cohort approach, period analysis and hybrid approach, and the survival status of different sex, urban and rural areas, cancer species and age groups were analyzed. Results: The age of 399 072 new cancer cases was (63.5±13.7) years old, with 57.77% (230 538 cases) about male and 32.89% (131 247 cases) from urban. During 2012-2014, 2015-2017 and 2018-2020, the 5-year cancer survival rates in Shandong Province were 32.3%, 34.7% and 40.2%, respectively. In 2018-2020, the first five cancers with survival rates were thyroid cancer (86.0%), breast cancer (78.2%), testicular cancer (75.7%), bladder cancer (70.3%) and uterine cancer (69.2%), and the last five cancers with survival rates were pancreatic cancer (15.5%), liver cancer (16.8%), gallbladder cancer (19.6%), bone cancer (22.7%) and lung cancer (24.4%). The 5-year survival rate for cancer of women (47.8%) was higher than that of men (33.8%), and the rate of urban areas (45.7%) was higher than that of rural areas (37.3%) during 2018-2020. The first five cancers in men were thyroid (87.1%), testicular (75.7%), bladder (70.9%), kidney (65.6%) and prostate (62.8%) cancers, and the last five cancers were pancreatic (14.3%), liver (16.8%), gallbladder (18.2%), bone (19.9%) and lung (21.7%) cancers. The first five cancers in women were thyroid (85.5%), breast (78.0%), uterine (69.2%), bladder (68.8%) and kidney (66.8%) cancers, and the last five cancers were liver (17.2%), pancreatic (17.2%), gallbladder (22.0%), bone (27.2%) and lung (29.1%) cancers. Conclusion: The 5-year cancer survival rate in Shandong Province was on the rise from 2012 to 2018, and the survival rates of different cancers were different.
目的： 分析2012—2018年山东省肿瘤登记地区癌症5年相对生存率。 方法： 以山东省23个肿瘤登记点上报的2012—2018年期间新发的399 072例癌症登记病例作为研究对象，参照国际疾病分类第十次修订版，登记范围为全部恶性肿瘤（C00~C97、D45~D47）、中枢神经系统的良性肿瘤（D32~D33）和中枢神经系统的动态未定肿瘤（D42~D43）。采用被动和主动随访相结合的方法，获取肿瘤患者的生存情况，随访截至日期为 2020 年12月31日。将诊断年份分为2012—2014、2015—2017和2018—2020三个时期，分别采用队列法、现时生存和杂交法计算5年癌症生存率，同时分析不同性别、城乡、癌种及年龄组的生存状况。 结果： 399 072例新发癌症病例年龄为（63.5±13.7）岁；男性占57.77%（230 538例）；城市占32.89%（131 247例）。2012—2014、2015—2017和2018—2020年，山东省5年癌症生存率分别为32.3%、34.7%和40.2%。2018—2020年5年生存率较高的癌症依次为甲状腺癌（86.0%）、乳腺癌（78.2%）、睾丸癌（75.7%）、膀胱癌（70.3%）及子宫癌（69.2%），5年生存率较低的癌症依次为胰腺癌（15.5%）、肝癌（16.8%）、胆囊癌（19.6%）、骨肿瘤（22.7%）及肺癌（24.4%）。2018—2020年女性5年生存率（47.8%）高于男性（33.8%），城市地区（45.7%）高于农村地区（37.3%）。男性5年生存率前5位的癌症依次为甲状腺癌（87.1%）、睾丸癌（75.7%）、膀胱癌（70.9%）、肾癌（65.6%）及前列腺癌（62.8%），后5位的癌症依次为胰腺癌（14.3%）、肝癌（16.8%）、胆囊癌（18.2%）、骨癌（19.9%）及肺癌（21.7%）；女性5年生存率前5位的癌症依次为甲状腺癌（85.5%）、乳腺癌（78.0%）、子宫癌（69.2%）、膀胱癌（68.8%）及肾癌（66.8%），后5位的癌症依次为肝癌（17.2%）、胰腺癌（17.2%）、胆囊癌（22.0%）、骨肿瘤（27.2%）及肺癌（29.1%）。 结论： 2012—2018年山东省5年癌症生存率有上升趋势，不同癌症间的生存率存在差异。.