Metastatic bone disease: Early referral for multidisciplinary care

Amir Hossain Gahanbani Ardakani; Martina Faimali; Lukas Nystrom; Nathan Mesko; Muntzer Mughal; Howard Ware; Panagiotis Gikas

doi:10.3949/ccjm.89a.21062

Metastatic bone disease: Early referral for multidisciplinary care

Cleve Clin J Med. 2022 Jul 1;89(7):393-399. doi: 10.3949/ccjm.89a.21062.

Authors

Amir Hossain Gahanbani Ardakani¹, Martina Faimali², Lukas Nystrom³, Nathan Mesko⁴, Muntzer Mughal⁵, Howard Ware⁶, Panagiotis Gikas⁷

Affiliations

¹ Research Fellow, Department of Orthopaedic Surgery, Cleveland Clinic London, UK amir.ardakani1@nhs.net.
² Department of Orthopaedic Oncology, Royal National Orthopaedic Hospital, Stanmore, UK.
³ Department of Orthopaedic Surgery, Cleveland Clinic, Cleveland, OH; Associate Professor of Surgery, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH.
⁴ Associate Professor of Surgery, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH; Center Director, Musculoskeletal Oncology, Department of Orthopaedic Surgery, and Co-Director of Sarcoma Care, Cleveland Clinic, Cleveland, OH.
⁵ Director, Department of Surgical Oncology, Cleveland Clinic London, UK.
⁶ Director, Department of Orthopaedic Surgery, Cleveland Clinic London, UK.
⁷ Department of Orthopaedic Surgery, South West London Elective Orthopaedic Centre, London, UK; Department of Orthopaedic Surgery, Cleveland Clinic London, UK.

PMID: 35777838
DOI: 10.3949/ccjm.89a.21062

Abstract

It is estimated that more than half of all cancers develop bony metastases, exacting a substantial cost in terms of patient quality of life and healthcare expenses. Prompt diagnosis and management have been shown to reduce morbidity and costs. When a patient with a history of cancer presents with musculoskeletal pain, heightened awareness of the risk of bone metastasis should prompt immediate referral to an orthopedic specialist. A multidisciplinary approach is needed to identify an appropriate treatment plan for the patient based on the prognosis, fracture status, and extent of skeletal disease.

Publication types

Review

MeSH terms

Bone Neoplasms* / diagnosis
Bone Neoplasms* / therapy
Humans
Prognosis
Quality of Life*
Referral and Consultation