Biological functions of peptides from legumes in gastrointestinal health. A review legume peptides with gastrointestinal protection

J Food Biochem. 2022 Oct;46(10):e14308. doi: 10.1111/jfbc.14308. Epub 2022 Jun 30.

Abstract

Extensively consumed worldwide, legumes such as beans, soybeans, chickpeas, and peas represent a great source of protein. Legume-derived proteins provide bioactive peptides, small sequences of amino acids produced by enzymatic hydrolysis, gastrointestinal digestion, fermentation, or germination. Recent studies showed diverse biological effects of these peptides as antioxidants, antihypertensives, anti-inflammatory, antimicrobial, antithrombotic, antidiabetic, hypocholesterolemic, and even immunomodulators. These beneficial effects aid in preventing and treating chronic illnesses, particularly inflammatory disorders, obesity, and cardiovascular diseases. Thus, this work discusses these biological functions in gastrointestinal digestion health of bioactive peptides obtained from common beans, soybeans, chickpeas, peas, and other legumes. PRACTICAL APPLICATIONS: Knowledge of the nutraceutical properties of legumes can encourage the use of these seeds as ingredients in the development and design of functional foods.

Keywords: biological activities; biopeptides; gastrointestinal health; legumes; proteins.

Publication types

  • Review
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acids
  • Anti-Inflammatory Agents
  • Antihypertensive Agents
  • Cicer* / chemistry
  • Fabaceae* / chemistry
  • Fibrinolytic Agents
  • Glycine max / chemistry
  • Hypoglycemic Agents
  • Peptides / chemistry
  • Peptides / pharmacology
  • Pisum sativum / chemistry
  • Vegetables

Substances

  • Amino Acids
  • Anti-Inflammatory Agents
  • Antihypertensive Agents
  • Fibrinolytic Agents
  • Hypoglycemic Agents
  • Peptides