A case of 5-aminolevulinic acid photodynamic therapy(ALA-PDT)combined with surgery for the treatment of acne conglobata

Qing-Yun Wu; Qian Zhang; Wen-Bo Bu; Fang Fang

doi:10.1016/j.pdpdt.2022.102986

A case of 5-aminolevulinic acid photodynamic therapy(ALA-PDT)combined with surgery for the treatment of acne conglobata

Photodiagnosis Photodyn Ther. 2022 Sep:39:102986. doi: 10.1016/j.pdpdt.2022.102986. Epub 2022 Jun 24.

Authors

Qing-Yun Wu¹, Qian Zhang¹, Wen-Bo Bu², Fang Fang¹

Affiliations

¹ Department of Dermatologic Surgery, Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing, Jiangsu 210042, China.
² Department of Dermatologic Surgery, Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing, Jiangsu 210042, China. Electronic address: buwenbo@163.com.

PMID: 35760351
DOI: 10.1016/j.pdpdt.2022.102986

Abstract

We report the case of a 20-year-old man with acne conglobata (AC) who was treated with 5-aminolevulinic acid photodynamic therapy (ALA-PDT) sequentially to deroofing, and finally used fractional carbon dioxide laser for esthetic requirements, achieving satisfying results. AC is a severe form of acne vulgaris that can lead to significant scarring and has serious negative effects on a patient's psychological well-being and quality of life. Some cases are likely resistant to currently available treatments. This report describes a promising, and effective method for the treatment of AC.

Keywords: 5-aminolevulinic acid; Acne conglobata; Combination; Deroofing; Photodynamic therapy.

Publication types

Case Reports

MeSH terms

Acne Conglobata* / drug therapy
Acne Vulgaris* / drug therapy
Adult
Aminolevulinic Acid / therapeutic use
Humans
Male
Photochemotherapy* / methods
Photosensitizing Agents / therapeutic use
Quality of Life
Treatment Outcome
Young Adult

Substances

Photosensitizing Agents
Aminolevulinic Acid