The Alzheimer's disease GWAS risk alleles in the ABCA7 promoter and 5' region reduce ABCA7 expression

Acta Neuropathol. 2022 Sep;144(3):585-587. doi: 10.1007/s00401-022-02459-8. Epub 2022 Jun 27.
No abstract available

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Comment

MeSH terms

  • ATP-Binding Cassette Transporters / genetics
  • ATP-Binding Cassette Transporters / metabolism
  • Alleles
  • Alzheimer Disease* / genetics
  • Alzheimer Disease* / metabolism
  • Genetic Predisposition to Disease / genetics
  • Genome-Wide Association Study
  • Humans
  • Polymorphism, Single Nucleotide / genetics

Substances

  • ABCA7 protein, human
  • ATP-Binding Cassette Transporters