Pathogenesis of Chicken Astrovirus Related Illnesses

Abdullahi Abdullahi Raji; Abdul Rahman Omar

doi:10.3389/fvets.2022.899901

Pathogenesis of Chicken Astrovirus Related Illnesses

Front Vet Sci. 2022 Jun 10:9:899901. doi: 10.3389/fvets.2022.899901. eCollection 2022.

Authors

Abdullahi Abdullahi Raji¹, Abdul Rahman Omar²

Affiliations

¹ Department of Veterinary Pathology, Faculty of Veterinary Medicine, Usmanu Danfodiyo University Sokoto, Sokoto, Nigeria.
² Laboratory of Vaccine and Biomolecules, Institute of Bioscience and Department of Veterinary pathology and Microbiology Universiti Putra Malaysia, Serdang, Malaysia.

Abstract

Of the several known viruses, chicken astrovirus (CAstV) has been associated with diarrhea, runting-stunting syndrome, severe kidney disease, and gout, and white chick syndrome (WCS) in young broiler chicks. Discovered in 2004, CAstV consists of two genogroups with an expanding subgroup because of the diversity exhibited in its viral capsid sequence. Despite these findings, there exists a dearth of knowledge on its pathogenesis. This review highlights the pathogenesis and development of in vivo and in vitro models.

Keywords: animal model; chicken astrovirus; genotypes; pathogenesis; pathology.

Publication types

Review