Diagnostic Value of Radioisotope Cisternography Using 111In-DTPA in a Patient with Rhinorrhea and Purulent Meningitis

Medicina (Kaunas). 2022 May 26;58(6):714. doi: 10.3390/medicina58060714.

Abstract

Cerebrospinal fluid (CSF) leakage is a rare condition. Prompt diagnosis and early treatment of CSF leakage minimizes the risk of severe complications such as bacterial meningitis. Different diagnostic modalities are used to detect the site of CSF leakage but often with unreliable results. The literature offers limited evidence-based guidance on the diagnostic approach for rhinorrhea. Correct localization of the defect is the mainstay for successful surgical treatment. Herein, we describe a case of recurrent meningitis due to cranio-nasal fistula and rhinorrhea successfully localized with radioisotope cisternography (RIC). We provide a detailed and practical overview of the RIC procedure and compare different imaging modalities used to detect the site of CSF leakage.

Keywords: cisternography; meningitis; rhinorrhea.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Cerebrospinal Fluid Rhinorrhea* / diagnostic imaging
  • Cerebrospinal Fluid Rhinorrhea* / surgery
  • Humans
  • Meningitis, Bacterial* / diagnostic imaging
  • Pentetic Acid
  • Radioisotopes
  • Rhinorrhea

Substances

  • Radioisotopes
  • Pentetic Acid

Grants and funding

This research received no external funding.