Unilateral Transient Enhanced SEP during Integrated Multiparameter Neurophysiological Monitoring in a Newborn with Symptomatic Seizure

Sara Cavaliere; Silvia Lori; Maria Bastianelli; Cesarina Cossu; Simonetta Gabbanini; Carlo Dani; Giovanna Bertini

doi:10.3390/pediatric14020033

Unilateral Transient Enhanced SEP during Integrated Multiparameter Neurophysiological Monitoring in a Newborn with Symptomatic Seizure

Pediatr Rep. 2022 May 27;14(2):254-261. doi: 10.3390/pediatric14020033.

Authors

Sara Cavaliere¹, Silvia Lori², Maria Bastianelli², Cesarina Cossu², Simonetta Gabbanini², Carlo Dani¹, Giovanna Bertini¹

Affiliations

¹ Department of Neurosciences, Psychology, Drug Research and Children's Health, University of Florence, 50134 Florence, Italy.
² Neurophysiology Unit, Neuro-Musculo-Skeletal Department, Careggi University Hospital, 50134 Florence, Italy.

Abstract

During Integrated Multiparametric Neurophysiological Monitoring (IMNA), a newborn with suspected hypoxia at birth and microhaemorrhagic and ischaemic lesions presented some clonic-tonic episodes with specific EEG patterns characterized by rolandic and temporal spikes and the appearance of a unilateral enhanced Somatosensory Evoked Potential (SEP) (10.45 µv). Since the literature does not seem to describe cases of giant SEP in newborns, in this case report, we will discuss the hypotheses underlying this potential. It could be assumed that the ischaemic and haemorrhagic lesions presented by the newborn may have developed as a result of neurotransmitter balance failure. This may be the origin of the EEG picture, which, consequently, could have triggered a potential with high amplitude.

Keywords: newborn; somatosensory evoked potential; unilateral enhanced SEP.

Publication types

Case Reports

Grants and funding

This research received no external funding.