Hypomelanosis of Ito

Abstract

Hypomelanosis of Ito is a rare neurocutaneous syndrome characterized by presence of hypopigmented skin lesions arranged in whorls and streaks following the lines of Blaschko and are often accompanied by abnormalities of the central nervous system, skeletal system, eyes and teeth. Additional symptoms include deafness, hemihypertrophy, cardiac abnormalities, renal malformations, and abnormalities of the genitourinary tract.

Keywords: Hypomelanosis of Ito; Ichthyosis with confetti, Klippel-Trenaunay syndrome; Incontinentia pigmenti achromians mosaic; Pallister-Killian mosaic syndrome.