Direct observation of a stable spiral wave reentry in ventricles of a whole human heart using optical mapping for voltage and calcium

Ilija Uzelac; Shahriar Iravanian; Neal K Bhatia; Flavio H Fenton

doi:10.1016/j.hrthm.2022.06.015

Direct observation of a stable spiral wave reentry in ventricles of a whole human heart using optical mapping for voltage and calcium

Heart Rhythm. 2022 Nov;19(11):1912-1913. doi: 10.1016/j.hrthm.2022.06.015. Epub 2022 Jun 16.

Authors

Ilija Uzelac¹, Shahriar Iravanian², Neal K Bhatia², Flavio H Fenton³

Affiliations

¹ School of Physics, Georgia Institute of Technology, Atlanta, Georgia.
² Division of Cardiology, Section of Electrophysiology, Emory University Hospital, Atlanta, Georgia.
³ School of Physics, Georgia Institute of Technology, Atlanta, Georgia; Division of Cardiology, Section of Electrophysiology, Emory University Hospital, Atlanta, Georgia. Electronic address: flavio.fenton@physics.gatech.edu.

PMID: 35716855
DOI: 10.1016/j.hrthm.2022.06.015

No abstract available

Keywords: Explanted human heart; Functional reentry; Langendorff-perfused whole human heart; Optical mapping human heart; Reentry; Spiral wave; Ventricular fibrillation; Ventricular tachycardia.

MeSH terms

Action Potentials
Calcium*
Heart Ventricles / diagnostic imaging
Humans
Tachycardia, Ventricular* / diagnosis
Tachycardia, Ventricular* / surgery

Substances

Calcium

Grants and funding

R01 HL143450/HL/NHLBI NIH HHS/United States