AT-HOOK MOTIF NUCLEAR LOCALIZED (AHL) proteins of ancient origin radiate new functions

Int J Biol Macromol. 2022 Aug 1:214:290-300. doi: 10.1016/j.ijbiomac.2022.06.100. Epub 2022 Jun 15.

Abstract

AHL (AT-HOOK MOTIF NUCLEAR LOCALIZED) protein is an important transcription factor in plants that regulates a wide range of biological process. It is considered to have evolved from an independent PPC domain in prokaryotes to a complete protein in modern plants. AT-hook motif and PPC conserved domains are the main functional domains of AHL. Since the discovery of AHL, their evolution and function have been continuously studied. The AHL gene family has been identified in multiple species and the functions of several members of the gene family have been studied. Here, we summarize the evolution and structural characteristics of AHL genes, and emphasize their biological functions. This review will provide a basis for further functional study and crop breeding.

Keywords: AHL; AT-hook; Evolution; Function; Regulation.

Publication types

  • Review

MeSH terms

  • AT-Hook Motifs* / genetics
  • Arabidopsis Proteins* / genetics
  • Cell Nucleus / genetics
  • Cell Nucleus / metabolism
  • Plant Breeding
  • Plant Proteins / genetics
  • Plant Proteins / metabolism

Substances

  • Arabidopsis Proteins
  • Plant Proteins