Drugging inflammation: Easier NSAID than done

Nicoletta Caronni; Renato Ostuni

doi:10.1016/j.immuni.2022.05.009

Drugging inflammation: Easier NSAID than done

Immunity. 2022 Jun 14;55(6):973-975. doi: 10.1016/j.immuni.2022.05.009.

Authors

Nicoletta Caronni¹, Renato Ostuni²

Affiliations

¹ San Raffaele Telethon Institute for Gene Therapy (SR-Tiget), IRCCS San Raffaele Scientific Institute, Milan, Italy.
² San Raffaele Telethon Institute for Gene Therapy (SR-Tiget), IRCCS San Raffaele Scientific Institute, Milan, Italy; Vita-Salute San Raffaele University, Milan, Italy. Electronic address: ostuni.renato@hsr.it.

PMID: 35704999
DOI: 10.1016/j.immuni.2022.05.009

Abstract

In this issue of Immunity, Eisenstein, Hiliard, et al., uncover a novel mechanism of some widely used non-steroidal anti-inflammatory drugs (NSAIDs): activation of the antioxidant transcription factor NRF2 in myeloid immune cells.

Publication types

Research Support, Non-U.S. Gov't
Comment

MeSH terms

Anti-Inflammatory Agents, Non-Steroidal* / therapeutic use
Humans
Inflammation*

Substances

Anti-Inflammatory Agents, Non-Steroidal