Sodium Tetradecyl Sulphate Sclerotherapy for Lateral Malleolar Bursitis of the Ankle

Clin Orthop Surg. 2022 Jun;14(2):289-296. doi: 10.4055/cios21182. Epub 2022 Apr 11.

Abstract

Background: The aim of this study was to evaluate clinical outcomes of sodium tetradecyl sulphate (STS) sclerotherapy for conservative treatment of lateral malleolar bursitis of the ankle.

Methods: We reviewed data from 20 consecutive patients (20 ankles) who underwent STS sclerotherapy between August 2018 and June 2019. After aspiration of fluid from the lateral malleolar bursal sac, 2 mL (20 mg) STS was injected into the sac. Clinical outcomes and side effects and complications were evaluated at 2 weeks, 3 months, 1 year, and 2 years after sclerotherapy. Responses to treatment were assessed according to degree of fluctuation, shrinkage of the bursal sac, and soft-tissue swelling. The 36-item short form survey (SF-36) was completed for each patient before and after therapy.

Results: Complete response was observed in 17 patients (85%), and partial response was observed in 3 patients (15%) after STS sclerotherapy. SF-36 physical component scores improved from 62.2 (interquartile range, 5.2) before therapy to 70.0 (interquartile range, 7.9) at last follow-up (p < 0.05). One patient (5%) experienced transient hyperpigmentation at the injection site. No major complications occurred.

Conclusions: STS sclerotherapy was an effective and safe treatment for patients with lateral malleolar bursitis of the ankle.

Keywords: Bursitis; Lateral malleolus; Sclerotherapy; Sodium tetradecyl sulphate.

MeSH terms

  • Ankle
  • Bursitis* / therapy
  • Humans
  • Sclerosing Solutions / adverse effects
  • Sclerosing Solutions / therapeutic use
  • Sclerotherapy
  • Sodium Tetradecyl Sulfate* / adverse effects
  • Sodium Tetradecyl Sulfate* / therapeutic use

Substances

  • Sclerosing Solutions
  • Sodium Tetradecyl Sulfate