EpCAM deficiency causes premature aging of intestinal epithelium via hyperactivating mTORC1 pathway

Clin Transl Med. 2022 Jun;12(6):e903. doi: 10.1002/ctm2.903.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aging, Premature* / metabolism
  • Epithelial Cell Adhesion Molecule / genetics
  • Epithelial Cell Adhesion Molecule / metabolism
  • Humans
  • Intestinal Mucosa / metabolism
  • Mechanistic Target of Rapamycin Complex 1 / genetics
  • Mechanistic Target of Rapamycin Complex 1 / metabolism

Substances

  • EPCAM protein, human
  • Epithelial Cell Adhesion Molecule
  • Mechanistic Target of Rapamycin Complex 1