Severe Cardiovascular Complications Following Liver Transplantation in Patients With Iron Overload

June-Wha Rhee; Sophia Zhang; Amy Gallo; Aijaz Ahmed; Masataka Kawana

doi:10.1016/j.jaccas.2021.12.012

Severe Cardiovascular Complications Following Liver Transplantation in Patients With Iron Overload

JACC Case Rep. 2022 Jun 1;4(11):677-681. doi: 10.1016/j.jaccas.2021.12.012.

Authors

June-Wha Rhee^{1

2}, Sophia Zhang¹, Amy Gallo³, Aijaz Ahmed⁴, Masataka Kawana¹

Affiliations

¹ Division of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, California, USA.
² City of Hope Comprehensive Cancer Center, Duarte, California, USA.
³ Division of Abdominal Transplantation, Department of Surgery, Stanford University School of Medicine, Stanford, California, USA.
⁴ Division of Gastroenterology and Hepatology, Department of Medicine, Stanford University School of Medicine, Stanford, California, USA.

Abstract

We report 4 cases of our institutional experience with liver transplantation that illustrate the high risk of heart failure and cardiogenic shock in the setting of cardiac iron overload. We then discuss a pragmatic approach to assess the cardiovascular risk in liver transplantation candidates with cardiac iron overload. (Level of Difficulty: Advanced.).

Keywords: CMR, cardiac magnetic resonance; ESLD, end-stage liver disease; HF, heart failure; LT, liver transplantation; LV, left ventricular; LVEF, left ventricular ejection fraction; cardiac iron overload; cardiac magnetic resonance; cardiovascular complications; liver transplantation; preoperative cardiovascular risk assessment.

Publication types

Case Reports