A Case of Upper Gastrointestinal Bleeding Due to Metastatic High-Grade B-Cell Lymphoma Successfully Treated With Chemotherapy

Samuel Tanner; Elie Al Kazzi; Rabail Aslam; Gerard Isenberg; Gregory Cooper

doi:10.7759/cureus.24738

A Case of Upper Gastrointestinal Bleeding Due to Metastatic High-Grade B-Cell Lymphoma Successfully Treated With Chemotherapy

Cureus. 2022 May 4;14(5):e24738. doi: 10.7759/cureus.24738. eCollection 2022 May.

Authors

Samuel Tanner¹, Elie Al Kazzi², Rabail Aslam³, Gerard Isenberg², Gregory Cooper²

Affiliations

¹ Department of Medicine, University Hospitals Cleveland Medical Center, Cleveland, USA.
² Division of Gastroenterology and Liver Disease, Department of Medicine, University Hospitals Cleveland Medical Center, Cleveland, USA.
³ Department of Pathology, University Hospitals Cleveland Medical Center, Cleveland, USA.

Abstract

Upper gastrointestinal bleeding (UGIB) is a common and potentially life-threatening condition. Metastatic disease is an exceedingly rare cause of UGIB. We report the case of a 73-year-old man with high-grade B-cell lymphoma (HGBL) who presented for the initiation of chemotherapy and was found to be acutely anemic due to UGIB. An esophagogastroduodenoscopy (EGD) revealed multiple large, discrete, ulcerated, non-circumferential, and friable masses in the stomach. Biopsies were consistent with HGBL. The patient was urgently initiated on chemotherapy with the resolution of lesions on subsequent EGD. The rate of prevalence of gastric metastases is unknown, but it should be considered in patients with active malignancy who present with signs of UGIB.

Keywords: endoscopy; gastric cancer; gastrointestinal hemorrhage; large b-cell lymphoma; lymphoma.

Publication types

Case Reports