Prediction of blood pressure changes associated with abdominal pressure changes during robotic laparoscopic low abdominal surgery using deep learning

PLoS One. 2022 Jun 6;17(6):e0269468. doi: 10.1371/journal.pone.0269468. eCollection 2022.

Abstract

Background: Intraoperative hypertension and blood pressure (BP) fluctuation are known to be associated with negative patient outcomes. During robotic lower abdominal surgery, the patient's abdominal cavity is filled with CO2, and the patient's head is steeply positioned toward the floor (Trendelenburg position). Pneumoperitoneum and the Trendelenburg position together with physiological alterations during anesthesia, interfere with predicting BP changes. Recently, deep learning using recurrent neural networks (RNN) was shown to be effective in predicting intraoperative BP. A model for predicting BP rise was designed using RNN under special scenarios during robotic laparoscopic surgery and its accuracy was tested.

Methods: Databases that included adult patients (over 19 years old) undergoing low abdominal da Vinci robotic surgery (ovarian cystectomy, hysterectomy, myomectomy, prostatectomy, and salpingo-oophorectomy) at Soonchunhyang University Bucheon Hospital from October 2018 to March 2021 were used. An RNN-based model was designed using Python3 language with the PyTorch packages. The model was trained to predict whether hypertension (20% increase in the mean BP from baseline) would develop within 10 minutes after pneumoperitoneum.

Results: Eight distinct datasets were generated and the predictive power was compared. The macro-average F1 scores of the datasets ranged from 68.18% to 72.33%. It took only 3.472 milliseconds to obtain 39 prediction outputs.

Conclusions: A prediction model using the RNN may predict BP rises during robotic laparoscopic surgery.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Blood Pressure / physiology
  • Deep Learning*
  • Female
  • Head-Down Tilt / adverse effects
  • Head-Down Tilt / physiology
  • Humans
  • Hypertension* / etiology
  • Laparoscopy* / adverse effects
  • Male
  • Pneumoperitoneum*
  • Pneumoperitoneum, Artificial / adverse effects
  • Robotic Surgical Procedures* / adverse effects
  • Young Adult

Grants and funding

This study was supported by the Soonchunhyang University Research Fund and the research grant of the Chungbuk National University in 2021. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.