Histomorphological Evaluation of Non-Neoplastic Lesions of Uterine Cervix and a Correlation of the Lesion with the Clinical Factors

Cardiovasc Hematol Agents Med Chem. 2023;21(1):31-41. doi: 10.2174/1871525720666220603111328.

Abstract

Aim: This study investigates the prevalence of non-malignant lesions of the cervix among various biopsy samples.

Methods: This case study consists of 50 cases of cervical biopsy over almost two years. The case history and clinical details of the patients were obtained.

Results: 60% of the cases that participated in this study reported white discharge per vaginum as a common clinical symptom. 4 cases (8%) showed koilocytic changes specific to the human papillomavirus during the study. Only 2% of the non-specific cervicitis showed lymphoid aggregates. Endocervical changes projected papillary endocervicitis with 9 cases (18%), squamous metaplasia with 7 cases (14%), and nabothian follicle cyst with 3 cases (6%).

Conclusion: It has been concluded that 50 cases were studied histologically, which had adequate representation of both ecto and endocervical tissue. Moreover, 31-40 years of age of patients showed the highest percentage of non-neoplastic lesions of the cervix when compared to other age groups.

Keywords: Uterine cervix; biopsy; clinical data; cytology; lesion; morphology.

MeSH terms

  • Cervix Uteri / pathology
  • Female
  • Humans
  • Uterine Cervical Neoplasms* / diagnosis
  • Uterine Cervical Neoplasms* / epidemiology
  • Uterine Cervical Neoplasms* / pathology
  • Uterine Cervicitis* / diagnosis
  • Uterine Cervicitis* / epidemiology
  • Uterine Cervicitis* / pathology