Neural Networks With Gated Recurrent Units Reduce Glucose Forecasting Error Due to Changes in Sensor Location

J Diabetes Sci Technol. 2024 Jan;18(1):124-134. doi: 10.1177/19322968221100839. Epub 2022 Jun 4.

Abstract

Background: Continuous glucose monitors (CGMs) have become important tools for providing estimates of glucose to patients with diabetes. Recently, neural networks (NNs) have become a common method for forecasting glucose values using data from CGMs. One method of forecasting glucose values is a time-delay feedforward (FF) NN, but a change in the CGM location on a participant can increase forecast error in a FF NN.

Methods: In response, we examined a NN with gated recurrent units (GRUs) as a method of reducing forecast error due to changes in sensor location.

Results: We observed that for 13 participants with type 2 diabetes wearing blinded CGMs on both arms for 12 weeks (FreeStyle Libre Pro-Abbott), GRU NNs did not produce significantly different errors in glucose prediction due to sensor location changes (P < .05).

Conclusion: We observe that GRU NNs can mitigate error in glucose prediction due to differences in CGM location.

Keywords: continuous glucose monitoring; gated recurrent unit; glucose forecast; neural network.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Blood Glucose
  • Blood Glucose Self-Monitoring / methods
  • Diabetes Mellitus, Type 2*
  • Forecasting
  • Glucose*
  • Humans
  • Neural Networks, Computer

Substances

  • Glucose
  • Blood Glucose