Nano-enabled plant-based colloidal delivery systems for bioactive agents in foods: Design, formulation, and application

Adv Colloid Interface Sci. 2022 Jul:305:102709. doi: 10.1016/j.cis.2022.102709. Epub 2022 May 26.

Abstract

Consumers are becoming increasingly aware of the impact of their dietary choices on the environment, animal welfare, and health, which is causing many of them to adopt more plant-based diets. For this reason, many sectors of the food industry are reformulating their products to contain more plant-based ingredients. This article describes recent research on the formation and application of nano-enabled colloidal delivery systems formulated from plant-based ingredients, such as polysaccharides, proteins, lipids, and phospholipids. These delivery systems include nanoemulsions, solid lipid nanoparticles, nanoliposomes, nanophytosomes, and biopolymer nanoparticles. The composition, size, structure, and charge of the particles in these delivery systems can be manipulated to create novel or improved functionalities, such as improved robustness, higher optical clarity, controlled release, and increased bioavailability. There have been major advances in the design, assembly, and application of plant-based edible nanoparticles within the food industry over the past decade or so. As a result, there are now a wide range of different options available for creating delivery systems for specific applications. In the future, it will be important to establish whether these formulations can be produced using economically viable methods and provide the desired functionality in real-life applications.

Keywords: Bioactive agent-delivery systems; Bioavailability; Colloidal systems; Functional nanomaterial; Phytochemicals.

Publication types

  • Review

MeSH terms

  • Animals
  • Drug Delivery Systems* / methods
  • Liposomes
  • Nanoparticle Drug Delivery System
  • Nanoparticles* / chemistry

Substances

  • Lipid Nanoparticles
  • Liposomes
  • Nanoparticle Drug Delivery System