The early-stage of primary pulmonary synovial sarcoma: A case report

Diana Rahmaniar; Daniel Maranatha

doi:10.1016/j.ijscr.2022.107251

The early-stage of primary pulmonary synovial sarcoma: A case report

Int J Surg Case Rep. 2022 Jun:95:107251. doi: 10.1016/j.ijscr.2022.107251. Epub 2022 May 24.

Authors

Diana Rahmaniar¹, Daniel Maranatha²

Affiliations

¹ Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Airlangga - Dr. Soetomo General Academic Hospital, Surabaya, Indonesia.
² Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Airlangga - Dr. Soetomo General Academic Hospital, Surabaya, Indonesia. Electronic address: daniel-maranatha@fk.unair.ac.id.

Abstract

Background: Primary pulmonary synovial sarcoma is a rare case of lung cancer. Surgical resection is standard therapy. Early-stage and complete resection offers a good prognosis.

Case presentation: A 50-year-old woman complained of intermittent left chest pain. Chest X-ray showed a mass around the heart, MSCT also showed enhanced solid lesion in the lower left lung anterobasal segment adhered to the pericardium. The patient underwent surgery with wedge resection with both immunohistochemical (IHC) EMA and CD99 positive. After surgery, she received 3-cycle chemotherapy that consisted of a combination of doxorubicin and ifosfamide.

Discussion: Surgical resection is the mainstay treatment for primary pulmonary synovial sarcoma. Chemotherapy can be considered for a patient with high-risk metastases. Early-stage and young age showed a good prognosis. Patient with stage IA still survives for 49 months after completing surgical resection and chemotherapy.

Conclusion: Resection of the tumor followed by chemotherapy may increase the survival tumor.

Keywords: Chemotherapy; Complete resection; Early-stage; Pulmonary synovial sarcoma.