A cationic iridium(III) complex containing a thiosemicarbazide unit: Synthesis and application for turn-on chemiluminescent detection of Hg2

Abstract

A novel cationic iridium(III) complex [(ppy)₂Ir(bPCPC)]PF₆ (ppy: 2-phenylpyridine; bPCPC: 2-([2,2'-bipyridine]-4-carbonyl)-N-phenylhydrazinecarbothioamide) containing a thiosemicarbazide unit was designed and synthesized. The thiosemicarbazide unit was a sensitive functional group to Hg²⁺, when it reacted with Hg²⁺, it was desulphurized and thus led to the formation of 1,3,4-oxadiazole, [(ppy)₂Ir(bPCPC)]PF₆ resultantly was used as a "turn-on" chemodosimeter for luminescent detection of Hg²⁺ in DMF/PBS buffer solution at pH = 7-11. Except for Ag⁺, recognition capability of [(ppy)₂Ir(bPCPC)]PF₆ to Hg²⁺ was not interfered by other common metal ions (Co²⁺, Li⁺, Zn²⁺, Pb²⁺, K⁺, Al³⁺, Na⁺, Mn²⁺, Cu²⁺, Fe²⁺, Fe³⁺, Cr³⁺, Ba²⁺, Mg²⁺, Ni²⁺ and Ca²⁺). The detection limit was 1.83 × 10^-9 mol∙L^-1 (0.37 ppb), which indicated the complex was a highly sensitive chemiluminescent detection reagent of Hg²⁺.

Keywords: Cationic iridium(III) complex; Chemiluminescent detection; Mercury(II) chemodosimeter; Thiosemicarbazide.