Association of Race and Ethnicity with Pediatric Postoperative Pain Outcomes

J Racial Ethn Health Disparities. 2023 Jun;10(3):1414-1422. doi: 10.1007/s40615-022-01327-1. Epub 2022 May 27.

Abstract

Introduction: Inequitable variability in healthcare practice negatively affects patient outcomes. Children of color may receive different analgesic medications in the perioperative period, resulting in different outcomes.

Methods: Medical records of children 0 to ≤ 18 years old from May 2014 to August 2019 were reviewed. The exposure was racial or ethnic groups: Asian, Black, Hispanic, Pacific Islander, and White non-Hispanic (reference).

Primary outcome: post-anesthesia care unit mean pain score.

Secondary outcomes: inpatient mean pain score; opioid, antiemetic, and antipruritic administration in the post-anesthesia care unit and inpatient ward. The association of race or ethnicity with outcomes was modeled using multilevel logistic regression, adjusting for confounders and covariates.

Results: Twenty-nine thousand six hundred fourteen cases are included. In the post-anesthesia care unit, Black, Hispanic, and Pacific Islander children had no significant difference in the odds of receiving opioids or having moderate-severe pain as compared to White non-Hispanic patients; Asian children had lower odds of receiving opioids and lower odds of having a moderate-severe mean pain score. In the inpatient setting, Black, Hispanic, and Pacific Islander children had no significant difference in the odds of receiving opioids or having moderate severe-pain as compared to White non-Hispanic children, but Asian children had lower odds of receiving opioids and of having a moderate-severe mean pain score.

Conclusions: Asian children had lower odds of receiving opioids and having moderate-severe pain postoperatively compared to the White non-Hispanic children. These differences may be a function of variation in patient/caregivers culture or healthcare provider care and warrant further investigation.

Keywords: Healthcare disparities; Pediatric anesthesia; Perioperative analgesia; Race and ethnicity.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, N.I.H., Extramural

MeSH terms

  • Adolescent
  • Analgesics
  • Analgesics, Opioid / therapeutic use
  • Asian
  • Black or African American
  • Child
  • Ethnicity*
  • Healthcare Disparities
  • Hispanic or Latino*
  • Humans
  • Pacific Island People
  • Pain, Postoperative
  • White

Substances

  • Analgesics
  • Analgesics, Opioid