PDA modified NIR-II NaEr0.8Yb0.2F4nanoparticles with high photothermal effect

Weifan Zhan; Bin Zhao; Xiaoxia Cui; Junsong Liu; Xusheng Xiao; Yantao Xu; Shengfei She; Chaoqi Hou; Haitao Guo

doi:10.1088/1361-6528/ac72b3

PDA modified NIR-II NaEr_0.8Yb_0.2F₄nanoparticles with high photothermal effect

Nanotechnology. 2022 Jun 28;33(38). doi: 10.1088/1361-6528/ac72b3.

Authors

Weifan Zhan^{1

2}, Bin Zhao³, Xiaoxia Cui^{1

2}, Junsong Liu⁴, Xusheng Xiao^{1

2}, Yantao Xu^{1

2}, Shengfei She^{1

2}, Chaoqi Hou^{1

2}, Haitao Guo^{1

2}

Affiliations

¹ Xi'an Institute of Optics and Fine Mechanics, Chinese Academy of Sciences, Xi'an Shanxi, People's Republic of China.
² Center for Materials Science and Optoelectronic Engineering, University of Chinese Academy of Sciences, Beijing, People's Republic of China.
³ Department of Sports Medicine, Fourth Medical Center, General Hospital of the Chinese People's Liberation Army, Chinese, Beijing, People's Republic of China.
⁴ Xi'an Department of Otolaryngology, Head and Neck Surgery, First Affiliated Hospital of Jiaotong University, Xi'an Shanxi, People's Republic of China.

PMID: 35609524
DOI: 10.1088/1361-6528/ac72b3

Abstract

Polydopamine (PDA)-modified NaEr_0.8Yb_{0.2 F4}nanoparticles were synthesized, with strong NIR-II emission, quantum yield of 29.63%, and excellent photothermal performance. Crystal phases and microstructures are characterized. Optical properties such as absorption, NIR-II emission, and light stability are studied, and the luminescence mechanism is discussed in detail. Key factors in NIR-II imaging were evaluated in fresh pork tissue, including penetration depth, spatial resolution, and signal-to-noise ratio (SNR). A high penetration depth of 5 mm and a high spatial resolution of 1 mm were detected. Mice are imaged in vivo afterintravenousinjection. Due to the accumulation of nanoparticles in the liver, high image quality with an SNR of 5.2 was detected in the abdomen of KM mice with hair. The photothermal conversion effect of PDA-modified NPs was twice that of the reported material. These NIR-II nanoparticles have superior optical properties, high photothermal efficiency and low cytotoxicity, and are potential fluorescent probes for further disease diagnosis and treatment.

Keywords: fluorescence imaging; light and heat; near-infrared-secondary; rare earth nanoparticles.

MeSH terms

Animals
Fluorescent Dyes / chemistry
Indoles
Mice
Nanoparticles* / chemistry
Phototherapy
Polymers* / chemistry

Substances

Fluorescent Dyes
Indoles
Polymers
polydopamine