Cystic pancreatic neuroendocrine tumours (cPNETs) are an uncommon diagnosis, representing less than 10% of all cystic neoplasms. They tend to affect patients aged between 30 and 60 years, with no differences between the sexes. Herein we present the case of a woman aged 75 years with a history of AHT, DM2 and CKF. Given symptoms of abdominal pain, toxic syndrome and altered hepatic analyses, the patient underwent an abdominal CT, which showed a solid mass with neoproliferative appearance in the pancreatic tail, along with a small, non-specific portacaval adenopathy. Consequently, an echo-endoscopy (USE) was performed to complete the study.