Infected Lower Limb Megaprosthesis on 68Ga-NOTA-Ubiquicidin PET/CT Imaging

Prateek Kaushik; Satya Dev Maurya; Nishikant Damle; Sanjana Ballal; Venkatesan Sampath Kumar; Chandrasekhar Bal; Madhavi Tripathi

doi:10.1007/s13139-022-00747-5

Infected Lower Limb Megaprosthesis on ⁶⁸Ga-NOTA-Ubiquicidin PET/CT Imaging

Nucl Med Mol Imaging. 2022 Jun;56(3):171-172. doi: 10.1007/s13139-022-00747-5. Epub 2022 Apr 11.

Authors

Prateek Kaushik¹, Satya Dev Maurya¹, Nishikant Damle¹, Sanjana Ballal¹, Venkatesan Sampath Kumar², Chandrasekhar Bal¹, Madhavi Tripathi¹

Affiliations

¹ Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, India.
² Department of Orthopaedics, All India Institute of Medical Sciences, New Delhi, India.

Abstract

Pain after prosthesis implant is a common clinical problem which requires distinction of septic from aseptic causes since the treatment differs. Non-invasive imaging methods play an important role in the diagnosis. Radiolabelled ubiquicidin can be used for imaging infection by binding directly to bacterial cell wall. We describe a case of a 24-year-old man with right lower limb megaprosthesis which did not show any loosening on computed tomography (CT) but was accurately diagnosed as infected prosthesis with ⁶⁸Ga-NOTA-ubiquicidin(29-41) acetate scan.

Keywords: 68Ga-NOTA-ubiquicidin; Infection; PET/CT; Prosthesis.