Modeling Approaches to Microbial Metabolism

Methods Mol Biol. 2022:2399:455-485. doi: 10.1007/978-1-0716-1831-8_17.

Abstract

Microbial systems are frequently used in biotechnology to convert substrates into valuable products. To make this efficient, knowledge on the specific metabolic characteristics of a system is required as well as a theoretical description that allows researchers to design the system for a profitable use in an industrial application. In this chapter, basics on mathematical modelling approaches are introduced and examples are provided.

Keywords: Coarse-grained modeling; Mass balance equation; Mathematical modeling; Stoichiometric networks.

MeSH terms

  • Biotechnology*
  • Models, Biological*
  • Models, Theoretical