Copper Cytotoxicity: Cellular Casualties of Noncognate Coordination Chemistry

mBio. 2022 Jun 28;13(3):e0043422. doi: 10.1128/mbio.00434-22. Epub 2022 May 23.

Abstract

Copper (Cu) is an essential micronutrient for cells, but in excess it is cytotoxic. How Cu is cytotoxic is the subject of recent work by L. Zuily, N.

Keywords: bacteria; copper; copper homeostasis; metalloenzyme; metalloprotein; mismetalation.

Publication types

  • Comment

MeSH terms

  • Antineoplastic Agents*
  • Copper* / toxicity

Substances

  • Antineoplastic Agents
  • Copper